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I Said Yes to Every Email for a Month! (Again)
How Claude is accelerating protein design and analytical chemistry
In this post, we share two results that show how Claude can help life scientists increase the pace of their research. In the first, we tested Claude’s ability to design protein binders from scratch, a key step in creating protein-based drugs that has historically taken a specialist weeks or months per target. In the second example, we evaluated whether Claude can accelerate chemical analysis. Claude Opus 5, a generally available model, was given NMR and LC-MS data (the data that allows chemists to assess the identity and purity of the compounds they work with).
Charts of the Week: Winds of Thematic Change
Winds of Thematic Change ETFs have become an increasingly prominent feature of public markets, especially for retail. Among other flavors, there are thematic ETFs, active and pass…
Konstantin Kisin's WARNING: Our Leaders Have Lost Control, We're Headed For Conflict And Violence!
Is the West collapsing, or is the planet? Political commentator Konstantin Kisin and rebel economist Steve Keen go head-to-head on the biggest questions facing the West: immigrati…
Anthropic
See allHow Claude is accelerating protein design and analytical chemistry
In this post, we share two results that show how Claude can help life scientists increase the pace of their research. In the first, we tested Claude’s ability to design protein binders from scratch, a key step in creating protein-based drugs that has historically taken a specialist weeks or months per target. In the second example, we evaluated whether Claude can accelerate chemical analysis. Claude Opus 5, a generally available model, was given NMR and LC-MS data (the data that allows chemists to assess the identity and purity of the compounds they work with).
Patterns and problems in multiagent systems
We ran experiments on swarms of Claude agents and found coordination failures, collusion, and sabotage. Here, we share what they mean for AI safety.
How well do job retraining programs work?
An evidence review from Anthropic's Economic Research team
Paul Graham
See allHow to Earn a Billion Dollars
(This is based on a talk I gave at the Oxford Union.) Since this is apparently the future prime ministers' club, I'm going to tell you about something it would be good if more politicians understood: I'm going to tell y…
Programming Bottom-Up
1993 (This essay is from the introduction to On Lisp .) Arc 's name.--> It's a long-standing principle of programming style that the functional elements of a program should not be too large. If some component of a progr…
What Languages Fix
Kevin Kelleher suggested an interesting way to compare programming languages: to describe each in terms of the problem it fixes. The surprising thing is how many, and how well, languages can be described this way. Algol…